Reconstruction and Regeneration

Our research in this program is seeking to develop innovative, biocompatible materials and technologies to repair the damage caused by oral disease by strengthening and regenerating tooth enamel, dentine and tissues.

The program includes two major projects:

  • Novel Biomaterials and Implants
  • Tissue Engineering and Regeneration

Novel Biomaterials and Implants

This project is researching new 'smart materials' or biomaterials that can be used to improve tooth restoration. Research in this project has led to the development of a new glass ionomer cement (Fuji VII-EP) that protects surrounding tooth enamel and dentine from demineralisation.

Dental implants are used to support artificial teeth, when one or more missing teeth need to be removed. Researchers within the Oral Health CRC are investigating better systems to regenerate bone following periodontal disease and tooth loss, which will allow better and more successful dental implants to take place. Researchers are also investigating how inflammation of tissue can be controlled during dental implant procedures to increase the success rates of implants.

Tissue Engineering and Regeneration

Tissue inflammation is a response to injury which is designed to minimise local damage. Most of this is short-lived but it can become persistent, with swelling, redness, heat, pain and loss of function. Chronic inflammation occurs in many diseases such as heart disease, cancer, diabetes and kidney disease. Researchers with the Oral Health CRC are investigating the role of tissue inflammation in periodontal disease and links with systemic diseases. By understanding and distinguishing the patient's inflammatory response, researchers are aiming to develop treatment options to effectively manage inflammation.